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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 40
Human Site: S314 Identified Species: 55
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S314 P H V P Y R E S K L T R I L Q
Chimpanzee Pan troglodytes XP_507923 1056 119132 S314 P H V P Y R E S K L T R I L Q
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 E162 S V K V S L L E I Y N E E L F
Dog Lupus familis XP_534964 1334 149091 S596 P H V P Y R E S K L T R I L Q
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S313 P H I P Y R E S K L T R I L Q
Rat Rattus norvegicus O55165 796 89797 Y105 Q T G T G K T Y T M Q G T W V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S293 G F V P Y R D S K L T R L L Q
Frog Xenopus laevis P28025 1060 119314 S307 P H I P Y R E S K L T R I L Q
Zebra Danio Brachydanio rerio NP_775368 955 106984 D264 I G K L N L V D L A G S E N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 S311 P H V P Y R E S K L T R L L Q
Honey Bee Apis mellifera XP_623508 706 80766 I15 K K E K K Q H I Q V F V R V R
Nematode Worm Caenorhab. elegans P46873 699 78760 A8 M A E S V R V A V R C R P F N
Sea Urchin Strong. purpuratus P46872 699 78679 N8 M P G G S S G N D N V R V V V
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 S339 G H I P Y R D S K L T R L L R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 S314 G H V P Y R D S K L T R L L R
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 S365 N H I P Y R E S K L T R L L Q
Red Bread Mold Neurospora crassa P48467 928 102392 A237 Q L F L V D L A G S E K V G K
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 100 N.A. 93.3 0 N.A. N.A. 73.3 93.3 0 N.A. 93.3 0 13.3 6.6
P-Site Similarity: 100 100 6.6 100 N.A. 100 13.3 N.A. N.A. 86.6 100 0 N.A. 100 33.3 20 26.6
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 66.6 N.A. N.A. 73.3 80 0
P-Site Similarity: 93.3 N.A. N.A. 93.3 93.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 0 0 0 0 12 0 6 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % C
% Asp: 0 0 0 0 0 6 18 6 6 0 0 0 0 0 0 % D
% Glu: 0 0 12 0 0 0 42 6 0 0 6 6 12 0 0 % E
% Phe: 0 6 6 0 0 0 0 0 0 0 6 0 0 6 6 % F
% Gly: 18 6 12 6 6 0 6 0 6 0 6 6 0 6 0 % G
% His: 0 53 0 0 0 0 6 0 0 0 0 0 0 0 0 % H
% Ile: 6 0 24 0 0 0 0 6 6 0 0 0 30 0 6 % I
% Lys: 6 6 12 6 6 6 0 0 59 0 0 6 0 0 6 % K
% Leu: 0 6 0 12 0 12 12 0 6 59 0 0 30 65 0 % L
% Met: 12 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % M
% Asn: 6 0 0 0 6 0 0 6 0 6 6 0 0 6 6 % N
% Pro: 36 6 0 59 0 0 0 0 0 0 0 0 6 0 0 % P
% Gln: 12 0 0 0 0 6 0 0 6 0 6 0 0 0 48 % Q
% Arg: 0 0 0 0 0 65 0 0 0 6 0 71 6 0 18 % R
% Ser: 6 0 0 6 12 6 0 59 0 6 0 6 0 0 0 % S
% Thr: 0 6 0 6 0 0 6 0 6 0 59 0 6 0 0 % T
% Val: 0 6 36 6 12 0 12 0 6 6 6 6 12 12 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % W
% Tyr: 0 0 0 0 59 0 0 6 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _